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Isoflurane-induced spatial memory impairment by a mechanism independent of amyloid-beta levels and tau protein phosphorylation changes in aged rats.
Liu W, Xu J, Wang H, Xu C, Ji C, Wang Y, Feng C, Zhang X, Xu Z, Wu A, Xie Z, Yue Y.
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WW domain-containing oxidoreductase promotes neuronal differentiation via negative regulation of glycogen synthase kinase 3β
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Endoplasmic reticulum stress: a new playER in tauopathies.
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Propyl isomerase Pin1 promotes APP protein turnover by inhibiting GSK3β kinase activity: A novel mechanism for Pin1 to protect against Alzheimer's disease.
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J Biol Chem. 2011 Dec 19. [Epub ahead of print]
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Effect of chronic administration of estradiol, progesterone, and tibolone on the expression and phosphorylation of glycogen synthase kinase-3β and the microtubule-associated protein tau in the hippocampus and cerebellum of female rat.
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Tau-Targeted Immunization Impedes Progression of Neurofibrillary Histopathology in Aged P301L Tau Transgenic Mice.
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Mechanistic involvement of the calpain-calpastatin system in Alzheimer neuropathology.
Higuchi M, Iwata N, Matsuba Y, Takano J, Suemoto T, Maeda J, Ji B, Ono M, Staufenbiel M, Suhara T, Saido TC.
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Autophagic degradation of tau in primary neurons and its enhancement by trehalose.
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Neurobiol Aging. 2011 Dec 12. [Epub ahead of print]
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Early Improved and Late Defective Cognition Is Reflected by Dendritic Spines in Tau.P301L Mice.
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Enriched odor exposure decrease tau phosphorylation in the rat hippocampus and cortex.
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Insights into Mitochondrial Dysfunction: Aging, Amyloid-β and Tau - a deleterious trio.
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Antioxid Redox Signal. 2011 Nov 27. [Epub ahead of print]
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Dyrk1A Positively Stimulates ASK1-JNK Signaling Pathway during Apoptotic Cell Death.
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Exp Neurobiol. 2011 Mar;20(1):35-44. Epub 2011 Mar 31.
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MED1 coactivation of androgen receptor-dependent transcription is mediated through a newly discovered noncanonical binding motif.
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J Biol Chem. 2011 Nov 18. [Epub ahead of print]
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Endoplasmic Reticulum Stress Induces Tau Pathology and Forms a Vicious Cycle: Implication in Alzheimer's Disease Pathogenesis.
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J Alzheimers Dis. 2011 Nov 18. [Epub ahead of print]
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Targeting Post-translational Modifications on Tau as a Therapeutic Strategy for Alzheimer's Disease.
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Cell Cycle Proteins in Brain in Mild Cognitive Impairment: Insights into Progression to Alzheimer Disease.
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Neurotox Res. 2011 Nov 15. [Epub ahead of print]
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SOD1 (Copper/Zinc Superoxide Dismutase) Deficiency Drives Amyloid β Protein Oligomerization and Memory Loss in Mouse Model of Alzheimer Disease.
Murakami K, Murata N, Noda Y, Tahara S, Kaneko T, Kinoshita N, Hatsuta H, Murayama S, Barnham KJ, Irie K, Shirasawa T, Shimizu T.
J Biol Chem. 2011 Dec 30;286(52):44557-68. Epub 2011 Nov 9.
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Structural characterization by nuclear magnetic resonance of the impact of phosphorylation in the proline-rich region of the disordered Tau protein.
Sibille N, Huvent I, Fauquant C, Verdegem D, Amniai L, Leroy A, Wieruszeski JM, Lippens G, Landrieu I.
Proteins. 2011 Sep 30. doi: 10.1002/prot.23210. [Epub ahead of print]
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Challenges associated with curcumin therapy in Alzheimer disease.
Belkacemi A, Doggui S, Dao L, Ramassamy C.
Expert Rev Mol Med. 2011 Nov 4;13:e34.
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Synaptic deficits are rescued in the p25/Cdk5 model of neurodegeneration by the reduction of β-secretase (BACE1).
Giusti-Rodríguez P, Gao J, Gräff J, Rei D, Soda T, Tsai LH.
J Neurosci. 2011 Nov 2;31(44):15751-6.
PMID: 22049418 [PubMed - indexed for MEDLINE]
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