gment of cellular prion, N1, protects against monomeric and oligomeric Aβ-associated cell death.
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Peripheral Administration of Antisense Targeting the Amyloid Beta Protein Precursor Reverses AβPP and LRP-1 Overexpression in the Aged SAMP8 Mouse Brain.
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The miR-124 regulates the expression of BACE1/β-secretase correlated with cell death in Alzheimer's disease.
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BACE1 Trafficking and Alzheimer's Disease Pathogenesis.
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Novel phenyl(thio)ureas bearing (thio)oxothiazoline group as potential BACE-1 inhibitors: synthesis and biological evaluation.
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A genome-wide study reveals rare CNVs exclusive to extreme phenotypes of Alzheimer disease.
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BETA-AMYLOID CARRYING THE DUTCH MUTATION HAS DIVERSE EFFECTS ON CALPAIN-MEDIATED TOXICITY IN HIPPOCAMPAL NEURONS.
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A Persistent Stress Response to Impeded Axonal Transport Leads to Accumulation of Amyloid-β in the Endoplasmic Reticulum, and Is a Probable Cause of Sporadic Alzheimer's Disease.
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Cellular Prion Protein Mediates Toxic Signaling of Amyloid Beta.
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Neurodegener Dis. 2011 Dec 9. [Epub ahead of print]
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Bispecific Tandem Single Chain Antibody Simultaneously Inhibits β-Secretase and Promotes α-Secretase Processing of AβPP.
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Putting proteins in their place: Palmitoylation in Huntington disease and other neuropsychiatric diseases.
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Prog Neurobiol. 2011 Dec 7. [Epub ahead of print]
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