Tau Proteins ~ TOP 100 Research Papers of Tau Proteins

Tau Proteins ~ TOP 100 Research Papers of Tau Proteins!!!!!

Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing

Yipeng Wang, Marta Martinez-Vicente, Ulrike Krüger, Susmita Kaushik, Esther Wong, Eva-Maria Mandelkow, Ana Maria Cuervo, Eckhard Mandelkow

Hum Mol Genet. 2009 November 1; 18(21): 4153–4170. Published online 2009 August 4.doi: 10.1093/hmg/ddp367

PMCID:: PMC2758146

Abstract Full Text PDF–734K Supplementary Material

Effect of Pin1 or Microtubule Binding on Dephosphorylation of FTDP-17 Mutant Tau

Kensuke Yotsumoto, Taro Saito, Akiko Asada, Takayuki Oikawa, Taeko Kimura, Chiyoko Uchida, Koichi Ishiguro, Takafumi Uchida, Masato Hasegawa, Shin-ichi Hisanaga

J Biol Chem. 2009 June 19; 284(25): 16840–16847. Published online 2009 April 28.doi: 10.1074/jbc.M109.003277

PMCID:: PMC2719320

Abstract Full Text Supplementary Material

Three Repeat Isoforms of Tau Inhibit Assembly of Four Repeat Tau Filaments

Stephanie J. Adams, Michael A. DeTure, Melinda McBride, Dennis W. Dickson, Leonard Petrucelli

PLoS One. 2010; 5(5): e10810. Published online 2010 May 25. doi: 10.1371/journal.pone.0010810

PMCID:: PMC2876030

Abstract Full Text PDF–1.4M

Blockade of NR2A-Containing NMDA Receptors Induces Tau Phosphorylation in Rat Hippocampal Slices

Julie Allyson, Eve Dontigny, Yves Auberson, Michel Cyr, Guy Massicotte

Neural Plast. 2010; 2010: 340168. Published online 2010 May 20. doi: 10.1155/2010/340168

PMCID:: PMC2874924

Abstract Full Text PDF–1.3M

The proline-rich domain of tau plays a role in interactions with actin

Hai Jin He, Xing Sheng Wang, Rong Pan, Dong Liang Wang, Ming Nan Liu, Rong Qiao He

BMC Cell Biol. 2009; 10: 81. Published online 2009 November 8. doi: 10.1186/1471-2121-10-81

PMCID:: PMC2784441

Abstract Full Text PDF–4.1M Supplementary Material

The Identification of Aminothienopyridazine Inhibitors of Tau Assembly by Quantitative High-Throughput Screening

Alex Crowe, Wenwei Huang, Carlo Ballatore, Ronald L. Johnson, Anne-Marie L. Hogan, Ruili Huang, Jennifer Wichterman, Joshua McCoy, Donna Huryn, Douglas S. Auld, Amos B. Smith, III, James Inglese, John Q. Trojanowski, Christopher P. Austin, Kurt R. Brunden, Virginia M.-Y. Lee

Biochemistry. Author manuscript; available in PMC 2010 August 18.

Published in final edited form as: Biochemistry. 2009 August 18; 48(32): 7732–7745.doi: 10.1021/bi9006435

PMCID:: PMC2773749

Abstract Full Text PDF–1.5M

Pseudo-hyperphosphorylation causing AD-like changes in tau has significant effects on its polymerization

Qian Sun, T. Chris Gamblin

Biochemistry. Author manuscript; available in PMC 2010 June 30.

Published in final edited form as: Biochemistry. 2009 June 30; 48(25): 6002–6011.doi: 10.1021/bi900602h

PMCID:: PMC2739831

Abstract Full Text PDF–3.3M

A role for FKBP52 in Tau protein function

Béatrice Chambraud, Elodie Sardin, Julien Giustiniani, Omar Dounane, Michael Schumacher, Michel Goedert, Etienne-Emile Baulieu

Proc Natl Acad Sci U S A. 2010 February 9; 107(6): 2658–2663. Published online 2010 January 25.doi: 10.1073/pnas.0914957107

PMCID:: PMC2823896

Abstract Full Text PDF–1.1M

A Possible Link Between Astrocyte Activation and Tau Nitration in Alzheimer's disease

Juan F. Reyes, Matthew R. Reynolds, Peleg M. Horowitz, Yifan Fu, Angela L. Guillozet-Bongaarts, Robert Berry, Lester I. Binder

Neurobiol Dis. Author manuscript; available in PMC 2009 October 23.

Published in final edited form as: Neurobiol Dis. 2008 August; 31(2): 198–208. Published online 2008 May 2. doi: 10.1016/j.nbd.2008.04.005

PMCID:: PMC2766349

Abstract Full Text PDF–1.7M

10.

VACCINATION AS A THERAPEUTIC APPROACH FOR ALZHEIMER’S DISEASE

Thomas Wisniewski, Allal Boutajangout

Mt Sinai J Med. Author manuscript; available in PMC 2011 January 25.

Published in final edited form as: Mt Sinai J Med. 2010 Jan-Feb; 77(1): 17–31. doi: 10.1002/msj.20156

PMCID:: PMC3026780

Abstract Full Text PDF–317K

11.

The Effect of a ΔK280 Mutation on the Unfolded State of a Microtubule-Binding Repeat in Tau

Austin Huang, Collin M. Stultz

PLoS Comput Biol. 2008 August; 4(8): e1000155. Published online 2008 August 22.doi: 10.1371/journal.pcbi.1000155

PMCID:: PMC2494868

Abstract Full Text PDF–642K

12.

Inhibition of tau fibrillization by oleocanthal via reaction with the amino groups of tau

Wenkai Li, Jeffrey B. Sperry, Alex Crowe, John Q. Trojanowski, Amos B. Smith, III, Virginia M.-Y. Lee

J Neurochem. Author manuscript; available in PMC 2010 August 1.

Published in final edited form as: J Neurochem. 2009 August; 110(4): 1339–1351. Published online 2009 June 15. doi: 10.1111/j.1471-4159.2009.06224.x

PMCID:: PMC2758489

Abstract Full Text PDF–651K Supplementary Material

13.

Two-Dimensional Electrophoresis of Tau Mutants Reveals Specific Phosphorylation Pattern Likely Linked to Early Tau Conformational Changes

Alexis Bretteville, Kunie Ando, Antoine Ghestem, Anne Loyens, Séverine Bégard, Jean-Claude Beauvillain, Nicolas Sergeant, Malika Hamdane, Luc Buée

PLoS ONE. 2009; 4(3): e4843. Published online 2009 March 17. doi: 10.1371/journal.pone.0004843

PMCID:: PMC2653646

Abstract Full Text PDF–256K

14.

Probing the biology of Alzheimer’s disease in mice

Karen H. Ashe, Kathleen R. Zahs

Neuron. Author manuscript; available in PMC 2011 June 10.

Published in final edited form as: Neuron. 2010 June 10; 66(5): 631–645.doi: 10.1016/j.neuron.2010.04.031

PMCID:: PMC2956420

Abstract Full Text PDF–1.6M Supplementary Material

15.

CSF phospho-tau correlates with behavioural decline and brain insoluble phospho-tau levels in a rat model of tauopathy

Norbert Zilka, Miroslava Korenova, Branislav Kovacech, Khalid Iqbal, Michal Novak

Acta Neuropathol. Author manuscript; available in PMC 2011 July 19.

Published in final edited form as: Acta Neuropathol. 2010 June; 119(6): 679–687. Published online 2010 April 9. doi: 10.1007/s00401-010-0680-3

PMCID:: PMC3139449

Abstract Full Text PDF–949K

16.

Expression, purification and crystallization of a human tau-tubulin kinase 2 that phosphorylates tau protein

Michiko Kitano-Takahashi, Hiroyuki Morita, Shin Kondo, Kayoko Tomizawa, Ryohei Kato, Michikazu Tanio, Yoshiko Shirota, Hiroshi Takahashi, Shigetoshi Sugio, Toshiyuki Kohno

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 July 1; 63(Pt 7): 602–604. Published online 2007 June 15. doi: 10.1107/S1744309107028783

PMCID:: PMC2335129

Abstract Full Text PDF–130K

17.

Multiple Events Lead to Dendritic Spine Loss in Triple Transgenic Alzheimer's Disease Mice

Tobias Bittner, Martin Fuhrmann, Steffen Burgold, Simon M. Ochs, Nadine Hoffmann, Gerda Mitteregger, Hans Kretzschmar, Frank M. LaFerla, Jochen Herms

PLoS One. 2010; 5(11): e15477. Published online 2010 November 16.doi: 10.1371/journal.pone.0015477

PMCID:: PMC2982845

Abstract Full Text PDF–1.9M Supplementary Material

18.

Human Stem Cell-Derived Neurons: A System to Study Human Tau Function and Dysfunction

Mariangela Iovino, Rickie Patani, Colin Watts, Siddharthan Chandran, Maria Grazia Spillantini

PLoS One. 2010; 5(11): e13947. Published online 2010 November 11.doi: 10.1371/journal.pone.0013947

PMCID:: PMC2978712

Abstract Full Text PDF–10M

19.

Vulnerabilities in the Tau Network and the Role of Ultrasensitive Points in Tau Pathophysiology

Theresa M. Yuraszeck, Pierre Neveu, Maria Rodriguez-Fernandez, Anne Robinson, Kenneth S. Kosik, Francis J. Doyle, III

PLoS Comput Biol. 2010 November; 6(11): e1000997. Published online 2010 November 11.doi: 10.1371/journal.pcbi.1000997

PMCID:: PMC2978700

Abstract Full Text PDF–731K Supplementary Material

20.

The Unfolded Protein Response Protects from Tau Neurotoxicity In Vivo

Carin A. Loewen, Mel B. Feany

PLoS One. 2010; 5(9): e13084. Published online 2010 September 29.doi: 10.1371/journal.pone.0013084

PMCID:: PMC2947516

Abstract Full Text PDF–1.5M Supplementary Material

21.

The estrogen receptor influences microtubule-associated protein tau (MAPT) expression and the selective estrogen receptor inhibitor fulvestrant downregulates MAPT and increases the sensitivity to taxane in breast cancer cells

Hirokuni Ikeda, Naruto Taira, Fumikata Hara, Takeo Fujita, Hiromasa Yamamoto, Junichi Soh, Shinichi Toyooka, Tomohiro Nogami, Tadahiko Shien, Hiroyoshi Doihara, Shinichiro Miyoshi

Breast Cancer Res. 2010; 12(3): R43. Published online 2010 June 28. doi: 10.1186/bcr2598

PMCID:: PMC2917038

Abstract Full Text PDF–1.6M

22.

Caspase activation precedes and leads to tangles

Alix de Calignon, Leora M. Fox, Rose Pitstick, George A. Carlson, Brian J. Bacskai, Tara L. Spires-Jones, Bradley T. Hyman

Nature. Author manuscript; available in PMC 2011 May 10.

Published in final edited form as: Nature. 2010 April 22; 464(7292): 1201–1204. Published online 2010 March 31. doi: 10.1038/nature08890

PMCID:: PMC3091360

Abstract Full Text PDF–610K Supplementary Material

23.

Characterization of tau fibrillization in vitro

Shaohua Xu, Kurt R. Brunden, John Q. Trojanowski, Virginia M.-Y. Lee

Alzheimers Dement. Author manuscript; available in PMC 2011 March 1.

Published in final edited form as: Alzheimers Dement. 2010 March; 6(2): 110–117.doi: 10.1016/j.jalz.2009.06.002

PMCID:: PMC2842604

Abstract Full Text PDF–1.0M

24.

Specification of Neuronal Polarity Regulated by Local Translation of CRMP2 and Tau via the mTOR-p70S6K Pathway

Tsuyoshi Morita, Kenji Sobue

J Biol Chem. 2009 October 2; 284(40): 27734–27745. Published online 2009 July 31.doi: 10.1074/jbc.M109.008177

PMCID:: PMC2785701

Abstract Full Text Supplementary Material

25.

Low Micromolar Zinc Accelerates the Fibrillization of Human Tau via Bridging of Cys-291 and Cys-322

Zhong-Ying Mo, Ying-Zhu Zhu, Hai-Li Zhu, Jun-Bao Fan, Jie Chen, Yi Liang

J Biol Chem. 2009 December 11; 284(50): 34648–34657. Published online 2009 October 13.doi: 10.1074/jbc.M109.058883

PMCID:: PMC2787327

Abstract Full Text

26.

Immunotherapeutic approaches for Alzheimer’s disease in transgenic mouse models

Thomas Wisniewski, Allal Boutajangout

Brain Struct Funct. Author manuscript; available in PMC 2011 June 27.

Published in final edited form as: Brain Struct Funct. 2010 March; 214(2-3): 201–218. Published online 2009 December 10. doi: 10.1007/s00429-009-0236-2

PMCID:: PMC3124148

Abstract Full Text PDF–398K

27.

Quantitative Characterization of Heparin Binding to Tau Protein: IMPLICATION FOR INDUCER-MEDIATED TAU FILAMENT FORMATION

Hai-Li Zhu, Cristina Fernández, Jun-Bao Fan, Frank Shewmaker, Jie Chen, Allen P. Minton, Yi Liang

J Biol Chem. 2010 February 5; 285(6): 3592–3599. Published online 2009 December 3.doi: 10.1074/jbc.M109.035691

PMCID:: PMC2824206

Abstract Full Text Supplementary Material

28.

The Prepared Tau Exon-Specific Antibodies Revealed Distinct Profiles of Tau in CSF of the Patients with Creutzfeldt-Jakob Disease

Cao Chen, Qi Shi, Bao-Yun Zhang, Gui-Rong Wang, Wei Zhou, Chen Gao, Chan Tian, Guo-Yong Mei, Yan-Ling Han, Jun Han, Xiao-Ping Dong

PLoS One. 2010; 5(7): e11886. Published online 2010 July 29. doi: 10.1371/journal.pone.0011886

PMCID:: PMC2912377

Abstract Full Text PDF–943K Supplementary Material

29.

Tau 6D and 6P isoforms inhibit polymerization of full-length tau in vitro

Nichole E. LaPointe, Peleg M. Horowitz, Angela L. Guillozet-Bongaarts, Andres Silva, Athena Andreadis, Lester I. Binder

Biochemistry. Author manuscript; available in PMC 2010 May 10.

Published in final edited form as: Biochemistry. 2009 December 29; 48(51): 12290–12297.doi: 10.1021/bi901304u

PMCID:: PMC2866057

Abstract Full Text PDF–563K

30.

Acceleration and persistence of neurofibrillary pathology in a mouse model of tauopathy following anesthesia

Emmanuel Planel, Alexis Bretteville, Li Liu, Laszlo Virag, Angela L. Du, Wai Haung Yu, Dennis W. Dickson, Robert A. Whittington, Karen E. Duff

FASEB J. 2009 August; 23(8): 2595–2604. doi: 10.1096/fj.08-122424

PMCID:: PMC2717763

Abstract Full Text

31.

Transmission and spreading of tauopathy in transgenic mouse brain

Florence Clavaguera, Tristan Bolmont, R. Anthony Crowther, Dorothee Abramowski, Stephan Frank, Alphonse Probst, Graham Fraser, Anna K. Stalder, Martin Beibel, Matthias Staufenbiel, Mathias Jucker, Michel Goedert, Markus Tolnay

Nat Cell Biol. Author manuscript; available in PMC 2010 January 1.

Published in final edited form as: Nat Cell Biol. 2009 July; 11(7): 909–913. Published online 2009 June 7. doi: 10.1038/ncb1901

PMCID:: PMC2726961

Abstract Full Text PDF–2.0M Supplementary Material

32.

Familial FTDP-17 Missense Mutations Inhibit Microtubule Assembly-promoting Activity of Tau by Increasing Phosphorylation at Ser²⁰²in Vitro

Dong Han, Hamid Y. Qureshi, Yifan Lu, Hemant K. Paudel

J Biol Chem. 2009 May 15; 284(20): 13422–13433. doi: 10.1074/jbc.M901095200

PMCID:: PMC2679442

Abstract Full Text Supplementary Material

33.

Physiological Transgene Regulation and Functional Complementation of a Neurological Disease Gene Deficiency in Neurons

Pier Paolo Peruzzi, Sean E Lawler, Steve L Senior, Nina Dmitrieva, Pauline AH Edser, Davide Gianni, E Antonio Chiocca, Richard Wade-Martins

Mol Ther. 2009 September; 17(9): 1517–1526. Published online 2009 April 7. doi: 10.1038/mt.2009.64

PMCID:: PMC2835262

Abstract Full Text PDF–505K Supplementary Material

34.

SUT-2 potentiates tau-induced neurotoxicity in Caenorhabditis elegans

Chris R. Guthrie, Gerard D. Schellenberg, Brian C. Kraemer

Hum Mol Genet. 2009 May 15; 18(10): 1825–1838. Published online 2009 March 9.doi: 10.1093/hmg/ddp099

PMCID:: PMC2722225

Abstract Full Text PDF–643K Supplementary Material

35.

Structural Polymorphism of 441-Residue Tau at Single Residue Resolution

Marco D Mukrasch, Stefan Bibow, Jegannath Korukottu, Sadasivam Jeganathan, Jacek Biernat, Christian Griesinger, Eckhard Mandelkow, Markus Zweckstetter

PLoS Biol. 2009 February; 7(2): e1000034. Published online 2009 February 17.doi: 10.1371/journal.pbio.1000034

PMCID:: PMC2642882

Abstract Full Text PDF–1.6M Supplementary Material

36.

Conformational Diversity of Wild-type Tau Fibrils Specified by Templated Conformation Change

Bess Frost, Julian Ollesch, Holger Wille, Marc I. Diamond

J Biol Chem. 2009 February 6; 284(6): 3546–3551. doi: 10.1074/jbc.M805627200

PMCID:: PMC2635036

Abstract Full Text Supplementary Material

37.

The Amino Terminus of Tau Inhibits Kinesin-Dependent Axonal Transport: Implications for Filament Toxicity

Nichole E. LaPointe, Gerardo Morfini, Gustavo Pigino, Irina N. Gaisina, Alan P. Kozikowski, Lester I. Binder, Scott T. Brady

J Neurosci Res. Author manuscript; available in PMC 2009 September 7.

Published in final edited form as: J Neurosci Res. 2009 February; 87(2): 440–451.doi: 10.1002/jnr.21850

PMCID:: PMC2739042

Abstract Full Text PDF–898K Supplementary Material

38.

Triple-transgenic Alzheimer's disease mice exhibit region-specific abnormalities in brain myelination patterns prior to appearance of amyloid and tau pathology

Maya K. Desai, Kelly L. Sudol, Michelle C. Janelsins, Michael A. Mastrangelo, Maria E. Frazer, William J. Bowers

Glia. Author manuscript; available in PMC 2010 January 1.

Published in final edited form as: Glia. 2009 January 1; 57(1): 54–65. doi: 10.1002/glia.20734

PMCID:: PMC2584762

Abstract Full Text PDF–853K

39.

A mutation affecting the sodium/proton exchanger, SLC9A6, causes mental retardation with tau deposition

James Y. Garbern, Manuela Neumann, John Q. Trojanowski, Virginia M.-Y. Lee, Gerald Feldman, Joy W. Norris, Michael J. Friez, Charles E. Schwartz, Roger Stevenson, Anders A. F. Sima

Brain. 2010 May; 133(5): 1391–1402. Published online 2010 April 15. doi: 10.1093/brain/awq071

PMCID:: PMC2859154

Abstract Full Text PDF–707K Supplementary Material

40.

Mechanisms of tau-induced neurodegeneration

Khalid Iqbal, Fei Liu, Cheng-Xin Gong, Alejandra del C. Alonso, Inge Grundke-Iqbal

Acta Neuropathol. Author manuscript; available in PMC 2010 May 18.

Published in final edited form as: Acta Neuropathol. 2009 July; 118(1): 53–69. Published online 2009 January 30. doi: 10.1007/s00401-009-0486-3

PMCID:: PMC2872491

Abstract Full Text PDF–740K

41.

Pathogenic missense MAPT mutations differentially modulate tau aggregation propensity at nucleation and extension steps

Edward Chang, Sohee Kim, Haishan Yin, Haikady N. Nagaraja, Jeff Kuret

J Neurochem. Author manuscript; available in PMC 2009 November 1.

Published in final edited form as: J Neurochem. 2008 November; 107(4): 1113–1123. Published online 2008 September 18. doi: 10.1111/j.1471-4159.2008.05692.x

PMCID:: PMC2596975

Abstract Full Text PDF–1.4M

42.

Tau aggregation and toxicity in tauopathic neurodegenerative diseases

Nicolette S. Honson, Jeff Kuret

J Alzheimers Dis. Author manuscript; available in PMC 2009 September 22.

Published in final edited form as: J Alzheimers Dis. 2008 August; 14(4): 417–422.

PMCID:: PMC2748882

Abstract Full Text PDF–298K

43.

Reduced early hypoxic/ischemic brain damage is associated with increased GLT-1 levels in mice expressing mutant (P301L) human tau

Guanghong Liao, Miou Zhou, Simon Cheung, James Galeano, Nam Nguyen, Michel Baudry, Xiaoning Bi

Brain Res. Author manuscript; available in PMC 2010 January 9.

Published in final edited form as: Brain Res. 2009 January 9; 1247: 159–170. Published online 2008 November 1. doi: 10.1016/j.brainres.2008.10.022

PMCID:: PMC2677806

Abstract Full Text PDF–1.4M

44.

Complementary dimerization of microtubule-associated tau protein: Implications for microtubule bundling and tau-mediated pathogenesis

Kenneth J. Rosenberg, Jennifer L. Ross, H. Eric Feinstein, Stuart C. Feinstein, Jacob Israelachvili

Proc Natl Acad Sci U S A. 2008 May 27; 105(21): 7445–7450. Published online 2008 May 21.doi: 10.1073/pnas.0802036105

PMCID:: PMC2396711

Abstract Full Text PDF–489K Supplementary Material

45.

Anesthesia-induced hyperphosphorylation detaches 3-repeat tau from microtubules without affecting their stability in vivo

Emmanuel Planel, Pavan Krishnamurthy, Tomohiro Miyasaka, Li Liu, Mathieu Herman, Asok Kumar, Alexis Bretteville, Helen Y. Figueroa, Wai Haung Yu, Robert A. Whittington, Peter Davies, Akihiko Takashima, Ralph A. Nixon, Karen E. Duff

J Neurosci. Author manuscript; available in PMC 2009 May 26.

Published in final edited form as: J Neurosci. 2008 November 26; 28(48): 12798–12807.doi: 10.1523/JNEUROSCI.4101-08.2008

PMCID:: PMC2610528

Abstract Full Text PDF–2.6M Supplementary Material

46.

Dissociation of tau toxicity and phosphorylation: role of GSK-3β, MARK and Cdk5 in aDrosophila model

Shreyasi Chatterjee, Tzu-Kang Sang, George M. Lawless, George R. Jackson

Hum Mol Genet. 2009 January 1; 18(1): 164–177. Published online 2008 October 17.doi: 10.1093/hmg/ddn326

PMCID:: PMC2644648

Abstract Full Text PDF–4.1M Supplementary Material

47.

The Last Tangle of Tau

Huiping Ding, Gail V.W. Johnson

J Alzheimers Dis. Author manuscript; available in PMC 2009 July 2.

Published in final edited form as: J Alzheimers Dis. 2008 August; 14(4): 441–447.

PMCID:: PMC2705238

Abstract Full Text PDF–177K

48.

The Microtubule-severing Proteins Spastin and Katanin Participate Differently in the Formation of Axonal Branches

Wenqian Yu, Liang Qiang, Joanna M. Solowska, Arzu Karabay, Sirin Korulu, Peter W. Baas

Mol Biol Cell. 2008 April; 19(4): 1485–1498. doi: 10.1091/mbc.E07-09-0878

PMCID:: PMC2291400

Abstract Full Text PDF–2.0M

49.

Detection of filamentous tau inclusions by the fluorescent Congo red derivative FSB [(trans,trans)-1-fluoro-2,5-bis(3-hydroxycarbonyl-4-hydroxy)styrylbenzene]

Ana Velasco, Graham Fraser, Patrice Delobel, Bernardino Ghetti, Isabelle Lavenir, Michel Goedert

FEBS Lett. 2008 March 19; 582(6): 901–906. doi: 10.1016/j.febslet.2008.02.025

PMCID:: PMC2726283

Abstract Full Text PDF–912K

50.

An inhibitor of tau hyperphosphorylation prevents severe motor impairments in tau transgenic mice

Sylvie Le Corre, Hans W. Klafki, Nikolaus Plesnila, Gabriele Hübinger, Axel Obermeier, Heidi Sahagún, Barbara Monse, Pierfausto Seneci, Jada Lewis, Jason Eriksen, Cynthia Zehr, Mei Yue, Eileen McGowan, Dennis W. Dickson, Michael Hutton, Hanno M. Roder

Proc Natl Acad Sci U S A. 2006 June 20; 103(25): 9673–9678. Published online 2006 June 12.doi: 10.1073/pnas.0602913103

PMCID:: PMC1480465

Abstract Full Text PDF–1.2M

51.

Immunotherapy Targeting Pathological Tau Protein in Alzheimer's Disease and Related Tauopathies

Einar M. Sigurdsson

J Alzheimers Dis. Author manuscript; available in PMC 2009 October 5.

Published in final edited form as: J Alzheimers Dis. 2008 October; 15(2): 157–168.

PMCID:: PMC2757121

Abstract Full Text PDF–145K

52.

Potency of a tau fibrillization inhibitor is influenced by its aggregation state

Erin E. Congdon, Mihaela Necula, Robert D. Blackstone, Jeff Kuret

Arch Biochem Biophys. Author manuscript; available in PMC 2008 September 1.

Published in final edited form as: Arch Biochem Biophys. 2007 September 1; 465(1): 127–135.Published online 2007 May 25. doi: 10.1016/j.abb.2007.05.004

PMCID:: PMC2048980

Abstract Full Text PDF–912K

53.

Binding to the Minor Groove of the Double-Strand, Tau Protein Prevents DNA from Damage by Peroxidation

Yan Wei, Mei-Hua Qu, Xing-Sheng Wang, Lan Chen, Dong-Liang Wang, Ying Liu, Qian Hua, Rong-Qiao He

PLoS ONE. 2008; 3(7): e2600. Published online 2008 July 2. doi: 10.1371/journal.pone.0002600

PMCID:: PMC2432501

Abstract Full Text PDF–951K

54.

Familial Prion Disease with Alzheimer Disease-Like Tau Pathology and Clinical Phenotype

Suman Jayadev, David Nochlin, Parvoneh Poorkaj, Ellen J. Steinbart, James A. Mastrianni, Thomas J. Montine, Bernardino Ghetti, Gerard D. Schellenberg, Thomas D. Bird, James B. Leverenz

Ann Neurol. Author manuscript; available in PMC 2011 June 14.

Published in final edited form as: Ann Neurol. 2011 April; 69(4): 712–720. Published online 2011 March 17. doi: 10.1002/ana.22264

PMCID:: PMC3114566

Abstract Full Text PDF–1.7M

55.

Contribution of complement activation pathways to neuropathology differs among mouse models of Alzheimer's disease

Maria I Fonseca, Shu-Hui Chu, Alisia M Berci, Marie E Benoit, Douglas G Peters, Yuko Kimura, Andrea J Tenner

J Neuroinflammation. 2011; 8: 4. Published online 2011 January 15. doi: 10.1186/1742-2094-8-4

PMCID:: PMC3033336

Abstract Full Text PDF–1.8M

56.

Identifying and validating biomarkers for Alzheimer's disease

Christian Humpel

Trends Biotechnol. 2011 January; 29(1): 26–32. doi: 10.1016/j.tibtech.2010.09.007

PMCID:: PMC3016495

Abstract Full Text PDF–116K

57.

Generation of a transgenic zebrafish model of Tauopathy using a novel promoter element derived from the zebrafish eno2 gene

Qing Bai, Jessica A. Garver, Neil A. Hukriede, Edward A. Burton

Nucleic Acids Res. 2007 October; 35(19): 6501–6516. Published online 2007 October.doi: 10.1093/nar/gkm608

PMCID:: PMC2095798

Abstract Full Text PDF–1.1M Supplementary Material

58.

Detection and Quantification of Tau Aggregation Using a Membrane Filter Assay

Edward Chang, Jeff Kuret

Anal Biochem. Author manuscript; available in PMC 2009 February 15.

Published in final edited form as: Anal Biochem. 2008 February 15; 373(2): 330–336. Published online 2007 September 19. doi: 10.1016/j.ab.2007.09.015

PMCID:: PMC2359897

Abstract Full Text PDF–445K

59.

Stepwise proteolysis liberates tau fragments that nucleate the Alzheimer-like aggregation of full-length tau in a neuronal cell model

Y. P. Wang, J. Biernat, M. Pickhardt, E. Mandelkow, E.-M. Mandelkow

Proc Natl Acad Sci U S A. 2007 June 12; 104(24): 10252–10257. Published online 2007 May 29.doi: 10.1073/pnas.0703676104

PMCID:: PMC1891218

Abstract Full Text PDF–1.1M Supplementary Material

60.

Tau in cerebrospinal fluid: a sensitive sandwich enzyme-linked immunosorbent assay using tyramide signal amplification

Hidenaga Yamamori, Sabiha Khatoon, Inge Grundke-Iqbal, Kaj Blennow, Michael Ewers, Harald Hampel, Khalid Iqbal

Neurosci Lett. Author manuscript; available in PMC 2007 August 23.

Published in final edited form as: Neurosci Lett. 2007 May 17; 418(2): 186–189. Published online 2007 March 14. doi: 10.1016/j.neulet.2007.03.022

PMCID:: PMC1950789

Abstract Full Text PDF–110K

61.

Pin1 has opposite effects on wild-type and P301L tau stability and tauopathy

Jormay Lim, Martin Balastik, Tae Ho Lee, Kazuhiro Nakamura, Yih-Cherng Liou, Anyang Sun, Greg Finn, Lucia Pastorino, Virginia M.-Y. Lee, Kun Ping Lu

J Clin Invest. 2008 May 1; 118(5): 1877–1889. Published online 2008 April 22. doi: 10.1172/JCI34308

PMCID:: PMC2323189

Abstract Full Text PDF–2.2M

62.

Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice

Jose F. Abisambra, Laura J. Blair, Shannon E. Hill, Jeffrey R. Jones, Clara Kraft, Justin Rogers, John Koren, III, Umesh K. Jinwal, Lisa Lawson, Amelia G. Johnson, Donna Wilcock, John C. O'Leary, Karen Jansen-West, Martin Muschol, Todd E. Golde, Edwin J. Weeber, Jessica Banko, Chad A. Dickey

J Neurosci. Author manuscript; available in PMC 2011 May 17.

Published in final edited form as: J Neurosci. 2010 November 17; 30(46): 15374–15382.doi: 10.1523/JNEUROSCI.3155-10.2010

PMCID:: PMC3073547

Abstract Full Text PDF–1.4M Supplementary Material

63.

Genetic background modifies neurodegeneration and neuroinflammation driven by misfolded human tau protein in rat model of tauopathy: implication for immunomodulatory approach to Alzheimer's disease

Zuzana Stozicka, Norbert Zilka, Petr Novak, Branislav Kovacech, Ondrej Bugos, Michal Novak

J Neuroinflammation. 2010; 7: 64. Published online 2010 October 12. doi: 10.1186/1742-2094-7-64

PMCID:: PMC2958906

Abstract Full Text PDF–5.6M

64.

eIF4A Inhibition Allows Translational Regulation of mRNAs Encoding Proteins Involved in Alzheimer's Disease

Andrew Bottley, Nicola M. Phillips, Thomas E. Webb, Anne E. Willis, Keith A. Spriggs

PLoS One. 2010; 5(9): e13030. Published online 2010 September 28.doi: 10.1371/journal.pone.0013030

PMCID:: PMC2946912

Abstract Full Text PDF–672K

65.

Novel therapeutics for Alzheimer's disease: An update

David J Bonda, Hyun-Pil Lee, Hyoung-gon Lee, Avi L Friedlich, George Perry, Xiongwei Zhu, Mark A Smith

Curr Opin Drug Discov Devel. Author manuscript; available in PMC 2011 March 1.

Published in final edited form as: Curr Opin Drug Discov Devel. 2010 March; 13(2): 235–246.

PMCID:: PMC2931269

Abstract Full Text PDF–349K

66.

Soluble amyloid β-protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration

Ming Jin, Nina Shepardson, Ting Yang, Gang Chen, Dominic Walsh, Dennis J. Selkoe

Proc Natl Acad Sci U S A. 2011 April 5; 108(14): 5819–5824. Published online 2011 March 18.doi: 10.1073/pnas.1017033108

PMCID:: PMC3078381

Abstract Full Text PDF–1.6M Supplementary Material

67.

Hyperphosphorylation and Aggregation of Tau in Laforin-deficient Mice, an Animal Model for Lafora Disease

Rajat Puri, Toshimitsu Suzuki, Kazuhiro Yamakawa, Subramaniam Ganesh

J Biol Chem. 2009 August 21; 284(34): 22657–22663. Published online 2009 June 19.doi: 10.1074/jbc.M109.009688

PMCID:: PMC2755673

Abstract Full Text Supplementary Material

68.

The MAP2/Tau family of microtubule-associated proteins

Leif Dehmelt, Shelley Halpain

Genome Biol. 2005; 6(1): 204. Published online 2004 December 23. doi: 10.1186/gb-2004-6-1-204

PMCID:: PMC549057

Abstract Full Text PDF–557K

69.

Immunotherapy targeting pathological tau prevents cognitive decline in a new tangle mouse model

Allal Boutajangout, David Quartermain, Einar M. Sigurdsson

J Neurosci. Author manuscript; available in PMC 2011 July 14.

Published in final edited form as: J Neurosci. 2010 December 8; 30(49): 16559–16566.doi: 10.1523/JNEUROSCI.4363-10.2010

PMCID:: PMC3135981

Abstract Full Text PDF–1.9M Supplementary Material

70.

Biguanide metformin acts on tau phosphorylation via mTOR/protein phosphatase 2A (PP2A) signaling

Eva Kickstein, Sybille Krauss, Paul Thornhill, Désirée Rutschow, Raphael Zeller, John Sharkey, Ritchie Williamson, Melanie Fuchs, Andrea Köhler, Hartmut Glossmann, Rainer Schneider, Calum Sutherland, Susann Schweiger

Proc Natl Acad Sci U S A. 2010 December 14; 107(50): 21830–21835. Published online 2010 November 22. doi: 10.1073/pnas.0912793107

PMCID:: PMC3003072

Abstract Full Text PDF–679K Supplementary Material

71.

Familial amyloid precursor protein mutants cause caspase-6-dependent but amyloid β-peptide-independent neuronal degeneration in primary human neuron cultures.

S N Sivananthan, A W Lee, C G Goodyer, A C LeBlanc

Cell Death Dis. 2010 November; 1(11): e100. Published online 2010 November 18.doi: 10.1038/cddis.2010.74

PMCID:: PMC3032318

Abstract Full Text PDF–676K Supplementary Material

72.

Alterations of brain and cerebellar proteomes linked to Aβ and tau pathology in a female triple-transgenic murine model of Alzheimer's disease

D Ciavardelli, E Silvestri, A Del Viscovo, M Bomba, D De Gregorio, M Moreno, C Di Ilio, F Goglia, L M T Canzoniero, S L Sensi

Cell Death Dis. 2010 October; 1(10): e90. Published online 2010 October 28.doi: 10.1038/cddis.2010.68

PMCID:: PMC3035905

Abstract Full Text PDF–646K Supplementary Material

73.

Silencing of CDK5 Reduces Neurofibrillary Tangles in Transgenic Alzheimer's Mice

Diego Piedrahita, Israel Hernández, Alejandro López-Tobón, Dmitry Fedorov, Boguslaw Obara, B.S. Manjunath, Ryan L Boudreau, Beverly Davidson, Frank LaFerla, Juan Carlos Gallego-Gómez, Kenneth S. Kosik, Gloria Patricia Cardona-Gómez

J Neurosci. Author manuscript; available in PMC 2011 April 20.

Published in final edited form as: J Neurosci. 2010 October 20; 30(42): 13966–13976.doi: 10.1523/JNEUROSCI.3637-10.2010

PMCID:: PMC3003593

Abstract Full Text PDF–1.4M

74.

Genome-wide association reveals genetic effects on human Aβ₄₂and τ protein levels in cerebrospinal fluids: a case control study

Mi-Ryung Han, Gerard D Schellenberg, Li-San Wang

BMC Neurol. 2010; 10: 90. Published online 2010 October 8. doi: 10.1186/1471-2377-10-90

PMCID:: PMC2964649

Abstract Full Text PDF–2.3M Supplementary Material

75.

Convergence of Presenilin- and Tau-mediated Pathways on Axonal Trafficking and Neuronal Function

Erica Peethumnongsin, Li Yang, Verena Kallhoff-Muñoz, Lingyun Hu, Akihiko Takashima, Robia G. Pautler, Hui Zheng

J Neurosci. Author manuscript; available in PMC 2011 April 6.

Published in final edited form as: J Neurosci. 2010 October 6; 30(40): 13409–13418.doi: 10.1523/JNEUROSCI.1964-10.2010

PMCID:: PMC2962595

Abstract Full Text PDF–1.1M Supplementary Material

76.

Therapeutic versus neuroinflammatory effects of passive immunization is dependent on Aβ/amyloid burden in a transgenic mouse model of Alzheimer's disease

S Sakura Minami, Elkhansa Sidahmed, Saba Aid, Mika Shimoji, Takako Niikura, Italo Mocchetti, G William Rebeck, Jay S Prendergast, Chris Dealwis, Ronald Wetzel, Francesca Bosetti, Yasuji Matsuoka, Hyang-Sook Hoe, R Scott Turner

J Neuroinflammation. 2010; 7: 57. Published online 2010 September 28. doi: 10.1186/1742-2094-7-57

PMCID:: PMC2955708

Abstract Full Text PDF–2.9M

77.

Selective Disruption of the Cerebral Neocortex in Alzheimer's Disease

Rahul S. Desikan, Mert R. Sabuncu, Nicholas J. Schmansky, Martin Reuter, Howard J. Cabral, Christopher P. Hess, Michael W. Weiner, Alessandro Biffi, Christopher D. Anderson, Jonathan Rosand, David H. Salat, Thomas L. Kemper, Anders M. Dale, Reisa A. Sperling, Bruce Fischl, the Alzheimer's Disease Neuroimaging Initiative

PLoS One. 2010; 5(9): e12853. Published online 2010 September 23.doi: 10.1371/journal.pone.0012853

PMCID:: PMC2944799

Abstract Full Text PDF–2.0M

78.

SNPs Associated with Cerebrospinal Fluid Phospho-Tau Levels Influence Rate of Decline in Alzheimer's Disease

Carlos Cruchaga, John S. K. Kauwe, Kevin Mayo, Noah Spiegel, Sarah Bertelsen, Petra Nowotny, Aarti R. Shah, Richard Abraham, Paul Hollingworth, Denise Harold, Michael M. Owen, Julie Williams, Simon Lovestone, Elaine R. Peskind, Ge Li, James B. Leverenz, Douglas Galasko, The Alzheimer's Disease Neuroimaging Initiative, John C. Morris, Anne M. Fagan, David M. Holtzman, Alison M. Goate

PLoS Genet. 2010 September; 6(9): e1001101. Published online 2010 September 16.doi: 10.1371/journal.pgen.1001101

PMCID:: PMC2940763

Abstract Full Text PDF–305K Supplementary Material

79.

Alzheimer's disease neurofibrillary degeneration: pivotal and multifactorial

Khalid Iqbal, Xiaochuan Wang, Julie Blanchard, Fei Liu, Cheng-Xin Gong, Inge Grundke-Iqbal

Biochem Soc Trans. Author manuscript; available in PMC 2011 May 11.

Published in final edited form as: Biochem Soc Trans. 2010 August; 38(4): 962–966.doi: 10.1042/BST0380962

PMCID:: PMC3092440

Abstract Full Text PDF–125K

80.

Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models

Janet van Eersel, Yazi D. Ke, Xin Liu, Fabien Delerue, Jillian J. Kril, Jürgen Götz, Lars M. Ittner

Proc Natl Acad Sci U S A. 2010 August 3; 107(31): 13888–13893. Published online 2010 July 19.doi: 10.1073/pnas.1009038107

PMCID:: PMC2922247

Abstract Full Text PDF–1.0M Supplementary Material

81.

Transgenic Expression of the Amyloid-β Precursor Protein-Intracellular Domain Does Not Induce Alzheimer's Disease–Like Traits In Vivo

Luca Giliberto, Cristina d'Abramo, Christopher Michael Acker, Peter Davies, Luciano D'Adamio

PLoS One. 2010; 5(7): e11609. Published online 2010 July 16. doi: 10.1371/journal.pone.0011609

PMCID:: PMC2905372

Abstract Full Text PDF–1.0M

82.

Association of the RAGE G82S polymorphism with Alzheimer’s disease

Jonny Daborg, Malin von Otter, Annica Sjölander, Staffan Nilsson, Lennart Minthon, Deborah R. Gustafson, Ingmar Skoog, Kaj Blennow, Henrik Zetterberg

J Neural Transm. 2010 July; 117(7): 861–867. Published online 2010 June 22. doi: 10.1007/s00702-010-0437-0

PMCID:: PMC2895876

Abstract Full Text PDF–210K

83.

Tau levels do not influence human ALS or motor neuron degeneration in the SOD1^G93Amouse

I. Taes, A. Goris, R. Lemmens, M.A. van Es, L.H. van den Berg, A. Chio, B.J. Traynor, A. Birve, P. Andersen, A. Slowik, B. Tomik, R.H. Brown, Jr., C.E. Shaw, A. Al-Chalabi, S. Boonen, L. Van Den Bosch, B. Dubois, P. Van Damme, W. Robberecht

Neurology. 2010 May 25; 74(21): 1687–1693. doi: 10.1212/WNL.0b013e3181e042f7

PMCID:: PMC2882212

Abstract Full Text PDF–1.8M Supplementary Material

84.

Why Pleiotropic Interventions are Needed for Alzheimer's Disease

Sally A. Frautschy, Greg M. Cole

Mol Neurobiol. 2010 June; 41(2-3): 392–409. Published online 2010 May 2. doi: 10.1007/s12035-010-8137-1

PMCID:: PMC2876259

Abstract Full Text PDF–753K

85.

Altered longevity-assurance activity of p53:p44 in the mouse causes memory loss, neurodegeneration and premature death

Mariana Pehar, Kenneth J O’Riordan, Melissa Burns-Cusato, Matthew E Andrzejewski, Carlos Gil del Alcazar, Corinna Burger, Heidi Scrable, Luigi Puglielli

Aging Cell. 2010 April; 9(2): 174–190. doi: 10.1111/j.1474-9726.2010.00547.x

PMCID:: PMC2848983

Abstract Full Text PDF–1.2M Supplementary Material

86.

Beneficial effect of human anti-amyloid-β active immunization on neurite morphology and tau pathology

Alberto Serrano-Pozo, Christopher M. William, Isidro Ferrer, Emmanuelle Uro-Coste, Marie-Bernadette Delisle, Claude-Alain Maurage, Christoph Hock, Roger M. Nitsch, Eliezer Masliah, John H. Growdon, Matthew P. Frosch, Bradley T. Hyman

Brain. 2010 May; 133(5): 1312–1327. Published online 2010 March 31. doi: 10.1093/brain/awq056

PMCID:: PMC2859150

Abstract Full Text PDF–1.1M Supplementary Material

87.

Transcriptome analysis of a tau overexpression model in rats implicates an early pro-inflammatory response

David B. Wang, Robert D. Dayton, Richard M. Zweig, Ronald L. Klein

Exp Neurol. Author manuscript; available in PMC 2011 July 1.

Published in final edited form as: Exp Neurol. 2010 July; 224(1): 197–206. Published online 2010 March 24. doi: 10.1016/j.expneurol.2010.03.011

PMCID:: PMC2906769

Abstract Full Text PDF–1.0M Supplementary Material

88.

Metastatic breast tumors express increased tau, which promotes microtentacle formation and the reattachment of detached breast tumor cells

Michael A. Matrone, Rebecca A. Whipple, Keyata Thompson, Edward H. Cho, Michele I. Vitolo, Eric M. Balzer, Jennifer R. Yoon, Olga B. Ioffe, Kimberly C. Tuttle, Ming Tan, Stuart S. Martin

Oncogene. Author manuscript; available in PMC 2011 July 9.

Published in final edited form as: Oncogene. 2010 June 3; 29(22): 3217–3227. Published online 2010 March 15. doi: 10.1038/onc.2010.68

PMCID:: PMC3132415

Abstract Full Text PDF–4.3M Supplementary Material

89.

Convergence of Amyloid-β and Tau Pathologies on Mitochondria In Vivo

Anne Eckert, Kathrin L. Schulz, Virginie Rhein, Jürgen Götz

Mol Neurobiol. 2010 June; 41(2-3): 107–114. Published online 2010 March 9. doi: 10.1007/s12035-010-8109-5

PMCID:: PMC2876263

Abstract Full Text PDF–265K

90.

Changes in dendritic complexity and spine morphology in transgenic mice expressing human wild-type tau

Dara L. Dickstein, Hannah Brautigam, Steven D. Stockton, Jr., James Schmeidler, Patrick R. Hof

Brain Struct Funct. Author manuscript; available in PMC 2011 February 2.

Published in final edited form as: Brain Struct Funct. 2010 March; 214(2-3): 161–179. Published online 2010 March 7. doi: 10.1007/s00429-010-0245-1

PMCID:: PMC3032082

Abstract Full Text PDF–915K

91.

Effect of Apolipoprotein E on Biomarkers of Amyloid Load and Neuronal Pathology in Alzheimer Disease

Prashanthi Vemuri, Heather J. Wiste, Stephen D. Weigand, David S. Knopman, Leslie M. Shaw, John Q. Trojanowski, Paul S. Aisen, Michael Weiner, Ronald C. Petersen, Clifford R. Jack, Jr., on behalf of the Alzheimer's Disease Neuroimaging Initiative

Ann Neurol. Author manuscript; available in PMC 2010 June 16.

Published in final edited form as: Ann Neurol. 2010 March; 67(3): 308–316. doi: 10.1002/ana.21953

PMCID:: PMC2886799

Abstract Full Text PDF–955K

92.

Molecular Interplay between Mammalian Target of Rapamycin (mTOR), Amyloid-β, and Tau: EFFECTS ON COGNITIVE IMPAIRMENTS

Antonella Caccamo, Smita Majumder, Arlan Richardson, Randy Strong, Salvatore Oddo

J Biol Chem. 2010 April 23; 285(17): 13107–13120. Published online 2010 February 23.doi: 10.1074/jbc.M110.100420

PMCID:: PMC2857107

Abstract Full Text Supplementary Material

93.

A DNA damage-activated checkpoint kinase phosphorylates tau and enhances tau-induced neurodegeneration

Kanae Iijima-Ando, LiJuan Zhao, Anthony Gatt, Christopher Shenton, Koichi Iijima

Hum Mol Genet. 2010 May 15; 19(10): 1930–1938. Published online 2010 February 16.doi: 10.1093/hmg/ddq068

PMCID:: PMC2860892

Abstract Full Text PDF–365K Supplementary Material

94.

Alzheimer Aβ Peptide Induces Chromosome Mis-Segregation and Aneuploidy, Including Trisomy 21: Requirement for Tau and APP

Antoneta Granic, Jaya Padmanabhan, Michelle Norden, Huntington Potter

Mol Biol Cell. 2010 February 15; 21(4): 511–520. doi: 10.1091/mbc.E09-10-0850

PMCID:: PMC2820417

Abstract Full Text PDF–1.0M

95.

Cerebrospinal fluid biomarkers of Alzheimer’s disease

Anne M Fagan, David M Holtzman

Biomark Med. Author manuscript; available in PMC 2010 December 1.

Published in final edited form as: Biomark Med. 2010 February; 4(1): 51–63. doi: 10.2217/BMM.09.83

PMCID:: PMC2846664

Abstract Full Text PDF–971K

96.

A Thorough Assessment of Benign Genetic Variability in GRN and MAPT

Rita J. Guerreiro, Nicole Washecka, John Hardy, Andrew Singleton

Hum Mutat. Author manuscript; available in PMC 2011 February 1.

Published in final edited form as: Hum Mutat. 2010 February; 31(2): E1126–E1140.doi: 10.1002/humu.21152

PMCID:: PMC2815037

Abstract Full Text PDF–305K Supplementary Material

97.

β-Amyloid_1–42 Gene Transfer Model Exhibits Intraneuronal Amyloid, Gliosis, Tau Phosphorylation, and Neuronal Loss

G. William Rebeck, Hyang-Sook Hoe, Charbel E.-H. Moussa

J Biol Chem. 2010 March 5; 285(10): 7440–7446. Published online 2010 January 13.doi: 10.1074/jbc.M109.083915

PMCID:: PMC2844192

Abstract Full Text

98.

Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease

Todd L. Edwards, William K. Scott, Cherylyn Almonte, Amber Burt, Eric H. Powell, Gary W. Beecham, Liyong Wang, Stephan Züchner, Ioanna Konidari, Gaofeng Wang, Carlos Singer, Fatta Nahab, Burton Scott, Jeffrey M. Stajich, Margaret Pericak-Vance, Jonathan Haines, Jeffery M. Vance, Eden R. Martin

Ann Hum Genet. Author manuscript; available in PMC 2011 March 1.

Published in final edited form as: Ann Hum Genet. 2010 March; 74(2): 97–109. Published online 2010 January 8. doi: 10.1111/j.1469-1809.2009.00560.x

PMCID:: PMC2853717

Abstract Full Text PDF–345K Supplementary Material

99.

Changes in the Expression of Genes Associated with Intraneuronal Amyloid Beta and Tau in Alzheimer's Disease

Robert K. Fujimura, Teresita Reiner, Fangchao Ma, Virginia Phillips, Alicia de las Pozas, Dennis W. Dickson, Bernard A. Roos, Guy A. Howard, Carlos Perez-Stable

J Alzheimers Dis. Author manuscript; available in PMC 2011 June 17.

Published in final edited form as: J Alzheimers Dis. 2010; 19(1): 97–109. doi: 10.3233/JAD-2010-1216

PMCID:: PMC3117045

Abstract Full Text PDF–876K

100.

The K_ATP Channel Activator Diazoxide Ameliorates Aβ and Tau Pathologies and Improves Memory in the 3xTgAD Mouse Model of Alzheimer's Disease

Dong Liu, Michael Pitta, Jong-Hwan Lee, Balmiki Ray, Debomoy Lahiri, Katsutoshi Furukawa, Mohamed Mughal, Haiyang Jiang, Julissa Villarreal, Roy G. Cutler, Nigel H. Greig, Mark P. Mattson

J Alzheimers Dis. Author manuscript; available in PMC 2010 November 19.

Published in final edited form as: J Alzheimers Dis. 2010 January 1; 22(2): 443–457. doi: 10.3233/JAD-2010-101017