Tau Protein Alzheimer's ~ Definition: Overview Research Papers on Tau Protein Alzheimer's

Tau Protein Alzheimer's ~ Definition: Overview Research Papers on Tau Protein Alzheimer's

Tau Protein Definition-I: A protein found in the axons of healthy neurons, where it binds to other proteins called microtubules to form the cytoskeleton of the neuron and provide the tracks over which material can be transported from one part of the neuron to another. http://www.answers.com/topic/tau-protein#ixzz1Vx45TwC7

Tau Protein Definition-II

(Biochemistry) a protein that maintains the stability of the microtubules that serve as a transport system within brain cells. It is also implicated in the formation of masses of fibrous protein in the brains of people with Alzheimer’s disease. http://www.science-dictionary.com/definition/tau-protein.html

Tau Protein Definition-III

A microtubule-associated protein that forms insoluble and hyperphosphorylated aggregates in Alzheimer's disease. http://medical-dictionary.thefreedictionary.com/tau+protein

Tau Protein Definition-IV 

(Science: cell biology) protein (60-70 kD) that co purifies with tubulin through cycles of assembly and disassembly and the first microtubule associated protein to be characterised. Tau proteins are a family made by alternative splicing of a single gene. It has tandem repeats of a tubulin binding domain and promotes tubulin assembly. Although tau proteins are found in all cells they are major components of neurons where they are predominantly associated with microtubules of the axon. http://www.biology-online.org/dictionary/Tau_protein

Tau Protein Definition-V 

Microtubule-associated proteins that are mainly expressed in neurons. Tau proteins constitute several isoforms and play an important role in the assembly of tubulin monomers into microtubules and in maintaining the cytoskeleton and axonal transport. Aggregation of specific sets of tau proteins in filamentous inclusions is the common feature of intraneuronal and glial fibrillar lesions (NEUROFIBRILLARY TANGLES; NEUROPIL THREADS) in numerous neurodegenerative disorders (ALZHEIMER DISEASE; TAUOPATHIES). http://medconditions.net/tau-protein.html

Research Papers on Tau Protein Alzheimer's

The Use of S100B and Tau Protein Concentrations in the Cerebrospinal Fluid for the Differential Diagnosis of Bacterial Meningitis: A Retrospective Analysis.

Jung K, Goerdt C, Lange P, Blocher J, Djukic M, Gerber J, Spreer A, Nau R, Otto M, Schmidt H.

Eur Neurol. 2011 Aug 25;66(3):128-132. [Epub ahead of print]

Insulin-induced neurite-like process outgrowth: Acceleration of tau protein synthesis via a phosphoinositide 3-kinase∼mammalian target of rapamycin pathway.

Nemoto T, Yanagita T, Satoh S, Maruta T, Kanai T, Murakami M, Wada A.

Neurochem Int. 2011 Aug 9.

Tau Protein and Alzheimer's Disease.

Maccioni RB.

Curr Alzheimer Res. 2011 Aug 9.

[Involvement of Cdk5/p35 and tau protein in the hippocampal mossy fiber sprouting in the PTZ kindling model].

Tian FF, Guo TH, Dang J, Ma YF, Chen JM, Chen Y, Cai XF, Song MY.

Zhonghua Yi Xue Za Zhi. 2011 May 10;91(17):1197-202. Chinese.

A case of anti-GA1 antibody-positive Fisher syndrome with elevated tau protein in cerebrospinal fluid.

Oyazato Y, Shiihara T, Kusunoki S, Adachi M, Ohnishi N, Taniguchi H, Nishiyama A, Watanabe A, Kobayashi M, Kamioka I.

Brain Dev. 2011 Jul 8.

Increased levels of total tau protein in the cerebrospinal fluid in Huntington's disease.

Constantinescu R, Romer M, Zetterberg H, Rosengren L, Kieburtz K.

Parkinsonism Relat Disord. 2011 Jul 4.

Assessment of cerebrospinal fluid (CSF) beta-amyloid (1-42), phosphorylated tau (ptau-181) and totalTau protein in patients with Alzheimer's disease (AD) and other dementia at Siriraj Hospital, Thailand.

Thaweepoksomboon J, Senanarong V, Poungvarin N, Chakorn T, Siwasariyanon N, Washirutmangkur L, Udompunthuruk S.

J Med Assoc Thai. 2011 Feb;94 Suppl 1:S77-83.

The role of Tau protein in resistance to paclitaxel.

Smoter M, Bodnar L, Duchnowska R, Stec R, Grala B, Szczylik C.

Cancer Chemother Pharmacol. 2011 Sep;68(3):553-557. Epub 2011 Jun 29.

Tau Protein Assembles into Isoform- and Disulfide-dependent Polymorphic Fibrils with Distinct Structural Properties.

Furukawa Y, Kaneko K, Nukina N.

J Biol Chem. 2011 Aug 5;286(31):27236-46. Epub 2011 Jun 9.

Passive immunization targeting pathological phospho-tau protein in a mouse model reduces functional decline and clears tau aggregates from the brain.

Boutajangout A, Ingadottir J, Davies P, Sigurdsson EM.

J Neurochem. 2011 Aug;118(4):658-67. doi: 10.1111/j.1471-4159.2011.07337.x. Epub 2011 Jul 1.

Structural memory of natively unfolded tau protein detected by small-angle X-ray scattering.

Shkumatov AV, Chinnathambi S, Mandelkow E, Svergun DI.

Proteins. 2011 Jul;79(7):2122-31. doi: 10.1002/prot.23033. Epub 2011 May 10.

Synergistic interactions between repeats in tau protein and Aβ amyloids may be responsible for accelerated aggregation via polymorphic states.

Miller Y, Ma B, Nussinov R.

Biochemistry. 2011 Jun 14;50(23):5172-81. Epub 2011 May 18.

Use of cerebrospinal fluid amyloid-β and total tau protein to predict favorable surgical outcomes in patients with idiopathic normal pressure hydrocephalus.

Tarnaris A, Toma AK, Chapman MD, Keir G, Kitchen ND, Watkins LD.

J Neurosurg. 2011 Jul;115(1):145-50. Epub 2011 Mar 25.

Dietary cholesterol and its effect on tau protein: a study in apolipoprotein E-deficient and P301L human tau mice.

Glöckner F, Meske V, Lütjohann D, Ohm TG.

J Neuropathol Exp Neurol. 2011 Apr;70(4):292-301.

Inhibition of phospholipase A(2) in rat brain decreases the levels of total Tau protein.

Schaeffer EL, De-Paula VJ, da Silva ER, de A Novaes B, Skaf HD, Forlenza OV, Gattaz WF.

J Neural Transm. 2011 Sep;118(9):1273-1279. Epub 2011 Mar 9.

Serum tau protein as a marker for the diagnosis of Creutzfeldt-Jakob disease.

Noguchi-Shinohara M, Hamaguchi T, Nozaki I, Sakai K, Yamada M.

J Neurol. 2011 Aug;258(8):1464-8. Epub 2011 Mar 1.

Identification of O-GlcNAc sites within peptides of the Tau protein and their impact on phosphorylation.

Smet-Nocca C, Broncel M, Wieruszeski JM, Tokarski C, Hanoulle X, Leroy A, Landrieu I, Rolando C, Lippens G, Hackenberger CP.

Mol Biosyst. 2011 May;7(5):1420-9. Epub 2011 Feb 16.

Macrocyclic β-sheet peptides that inhibit the aggregation of a tau-protein-derived hexapeptide.

Zheng J, Liu C, Sawaya MR, Vadla B, Khan S, Woods RJ, Eisenberg D, Goux WJ, Nowick JS.

J Am Chem Soc. 2011 Mar 9;133(9):3144-57. Epub 2011 Feb 14.

Local delivery of recombinant human bone morphogenetic protein-2 increases axonal regeneration and the expression of tau protein after facial nerve injury.

Wu G, Ju L, Jin T, Chen L, Shao L, Wang Y, Liu B.

J Int Med Res. 2010 Sep-Oct;38(5):1682-8.

Tau protein is required for amyloid {beta}-induced impairment of hippocampal long-term potentiation.

Shipton OA, Leitz JR, Dworzak J, Acton CE, Tunbridge EM, Denk F, Dawson HN, Vitek MP, Wade-Martins R, Paulsen O, Vargas-Caballero M.

J Neurosci. 2011 Feb 2;31(5):1688-92.

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17.

Identification of O-GlcNAc sites within peptides of the Tau protein and their impact on phosphorylation.

Smet-Nocca C, Broncel M, Wieruszeski JM, Tokarski C, Hanoulle X, Leroy A, Landrieu I, Rolando C, Lippens G, Hackenberger CP.

Mol Biosyst. 2011 May;7(5):1420-9. Epub 2011 Feb 16.

PMID:

 

21327254

 

[PubMed - in process]

Related citations

18.

Macrocyclic β-sheet peptides that inhibit the aggregation of a tau-protein-derived hexapeptide.

Zheng J, Liu C, Sawaya MR, Vadla B, Khan S, Woods RJ, Eisenberg D, Goux WJ, Nowick JS.

J Am Chem Soc. 2011 Mar 9;133(9):3144-57. Epub 2011 Feb 14.

PMID:

 

21319744

 

[PubMed - indexed for MEDLINE] 

Free PMC Article

Free full text Related citations

19.

Local delivery of recombinant human bone morphogenetic protein-2 increases axonal regeneration and the expression of tau protein after facial nerve injury.

Wu G, Ju L, Jin T, Chen L, Shao L, Wang Y, Liu B.

J Int Med Res. 2010 Sep-Oct;38(5):1682-8.

PMID:

 

21309482

 

[PubMed - indexed for MEDLINE]

Related citations

20.

Tau protein is required for amyloid {beta}-induced impairment of hippocampal long-term potentiation.

Shipton OA, Leitz JR, Dworzak J, Acton CE, Tunbridge EM, Denk F, Dawson HN, Vitek MP, Wade-Martins R, Paulsen O, Vargas-Caballero M.

J Neurosci. 2011 Feb 2;31(5):1688-92.

PMID:

 

21289177

 

[PubMed - indexed for MEDLINE] 

Free Article

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