Tau Protein Blog ~ Tau Protein Research Papers

Binding to the Minor Groove of the Double-Strand, Tau Protein Prevents DNA from Damage by Peroxidation

Yan Wei, Mei-Hua Qu, Xing-Sheng Wang, Lan Chen, Dong-Liang Wang, Ying Liu, Qian Hua, and Rong-Qiao He

PLoS ONE. 2008; 3(7): e2600. Published online 2008 July 2. doi: 10.1371/journal.pone.0002600

PMCID: 

PMC2432501

AbstractFull TextPDF–951K

2.

Ultrasensitive and Highly Selective Detection Of Alzheimer’s Disease Biomarker Using Two-Photon Rayleigh Scattering Properties of Gold Nanoparticle

Adria Neely, Candice Perry, Birsen Varisli, Anant K. Singh, Tahir Arbneshi, Dulal Senapati, Jhansi Rani Kalluri, and Paresh Chandra Ray

ACS Nano. Author manuscript; available in PMC 2010 September 22.

Published in final edited form as: ACS Nano. 2009 September 22; 3(9): 2834–2840. doi: 10.1021/nn900813b

PMCID: 

PMC2749966

AbstractFull TextPDF–2.0M

3.

Quantitative Characterization of Heparin Binding to Tau Protein: IMPLICATION FOR INDUCER-MEDIATED TAU FILAMENT FORMATION

Hai-Li Zhu, Cristina Fernández, Jun-Bao Fan, Frank Shewmaker, Jie Chen, Allen P. Minton, and Yi Liang

J Biol Chem. 2010 February 5; 285(6): 3592–3599. Published online 2009 December 3. doi: 10.1074/jbc.M109.035691

PMCID: 

PMC2824206

AbstractFull TextSupplementary Material

4.

Macrocyclic β-Sheet Peptides That Inhibit the Aggregation of a Tau-Protein-Derived Hexapeptide

Jing Zheng, Cong Liu, Michael R. Sawaya, Balraju Vadla, Shafiullah Khan, R. Jeremy Woods, David Eisenberg, Warren J. Goux, and James S. Nowick

J Am Chem Soc. 2011 March 9; 133(9): 3144–3157. Published online 2011 February 14. doi: 10.1021/ja110545h

PMCID: 

PMC3048834

AbstractFull TextPDF–6.6MSupplementary Material

5.

The Physiological Link between Metabolic Rate Depression and Tau Phosphorylation in Mammalian Hibernation

Jens T. Stieler, Torsten Bullmann, Franziska Kohl, Øivind Tøien, Martina K. Brückner, Wolfgang Härtig, Brian M. Barnes, and Thomas Arendt

PLoS One. 2011; 6(1): e14530. Published online 2011 January 18. doi: 10.1371/journal.pone.0014530

PMCID: 

PMC3022585

AbstractFull TextPDF–1.9MSupplementary Material

6.

Expression, purification and crystallization of a human tau-tubulin kinase 2 that phosphorylates tau protein

Michiko Kitano-Takahashi, Hiroyuki Morita, Shin Kondo, Kayoko Tomizawa, Ryohei Kato, Michikazu Tanio, Yoshiko Shirota, Hiroshi Takahashi, Shigetoshi Sugio, and Toshiyuki Kohno

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 July 1; 63(Pt 7): 602–604. Published online 2007 June 15.doi: 10.1107/S1744309107028783

PMCID: 

PMC2335129

AbstractFull TextPDF–130K

7.

Genetic background modifies neurodegeneration and neuroinflammation driven by misfolded human tau protein in rat model of tauopathy: implication for immunomodulatory approach to Alzheimer's disease

Zuzana Stozicka, Norbert Zilka, Petr Novak, Branislav Kovacech, Ondrej Bugos, and Michal Novak

J Neuroinflammation. 2010; 7: 64. Published online 2010 October 12. doi: 10.1186/1742-2094-7-64

PMCID: 

PMC2958906

AbstractFull TextPDF–5.6M

8.

Physiological Transgene Regulation and Functional Complementation of a Neurological Disease Gene Deficiency in Neurons

Pier Paolo Peruzzi, Sean E Lawler, Steve L Senior, Nina Dmitrieva, Pauline AH Edser, Davide Gianni, E Antonio Chiocca, and Richard Wade-Martins

Mol Ther. 2009 September; 17(9): 1517–1526. Published online 2009 April 7. doi: 10.1038/mt.2009.64

PMCID: 

PMC2835262

AbstractFull TextPDF–505KSupplementary Material

9.

A role for FKBP52 in Tau protein function

Béatrice Chambraud, Elodie Sardin, Julien Giustiniani, Omar Dounane, Michael Schumacher, Michel Goedert, and Etienne-Emile Baulieu

Proc Natl Acad Sci U S A. 2010 February 9; 107(6): 2658–2663. Published online 2010 January 25.doi: 10.1073/pnas.0914957107

PMCID: 

PMC2823896

AbstractFull TextPDF–1.1M

10.

Pseudo-hyperphosphorylation causing AD-like changes in tau has significant effects on its polymerization

Qian Sun and T. Chris Gamblin

Biochemistry. Author manuscript; available in PMC 2010 June 30.

Published in final edited form as: Biochemistry. 2009 June 30; 48(25): 6002–6011. doi: 10.1021/bi900602h

PMCID: 

PMC2739831

AbstractFull TextPDF–3.3M

11.

Hyperphosphorylation and Aggregation of Tau in Laforin-deficient Mice, an Animal Model for Lafora Disease

Rajat Puri, Toshimitsu Suzuki, Kazuhiro Yamakawa, and Subramaniam Ganesh

J Biol Chem. 2009 August 21; 284(34): 22657–22663. Published online 2009 June 19. doi: 10.1074/jbc.M109.009688

PMCID: 

PMC2755673

AbstractFull TextSupplementary Material

12.

Low Micromolar Zinc Accelerates the Fibrillization of Human Tau via Bridging of Cys-291 and Cys-322

Zhong-Ying Mo, Ying-Zhu Zhu, Hai-Li Zhu, Jun-Bao Fan, Jie Chen, and Yi Liang

J Biol Chem. 2009 December 11; 284(50): 34648–34657. Published online 2009 October 13.doi: 10.1074/jbc.M109.058883

PMCID: 

PMC2787327

AbstractFull Text

13.

Clamp–Loader–Helicase Interaction in Bacillus. Leucine 381 Is Critical for Pentamerization and Helicase Binding of the Bacillus τ Protein

A. Haroniti, R. Till, M. C. M. Smith, and P. Soultanas

Biochemistry. Author manuscript; available in PMC 2011 February 7.

Published in final edited form as: Biochemistry. 2003 September 23; 42(37): 10955–10964. doi: 10.1021/bi034955g

PMCID: 

PMC3034353

AbstractFull TextPDF–874K

14.

Three Repeat Isoforms of Tau Inhibit Assembly of Four Repeat Tau Filaments

Stephanie J. Adams, Michael A. DeTure, Melinda McBride, Dennis W. Dickson, and Leonard Petrucelli

PLoS One. 2010; 5(5): e10810. Published online 2010 May 25. doi: 10.1371/journal.pone.0010810

PMCID: 

PMC2876030

AbstractFull TextPDF–1.4M

15.

Raised CSF phospho‐tau concentrations in variant Creutzfeldt–Jakob disease: diagnostic and pathological implications

C A Goodall, M W Head, D Everington, J W Ironside, R S G Knight, and A J E Green

J Neurol Neurosurg Psychiatry. 2006 January; 77(1): 89–91. doi: 10.1136/jnnp.2005.065755

PMCID: 

PMC2117383

AbstractFull TextPDF–166K

16.

Immunotherapy Targeting Pathological Tau Protein in Alzheimer's Disease and Related Tauopathies

Einar M. Sigurdsson

J Alzheimers Dis. Author manuscript; available in PMC 2009 October 5.

Published in final edited form as: J Alzheimers Dis. 2008 October; 15(2): 157–168.

PMCID: 

PMC2757121

AbstractFull TextPDF–145K

17.

Complementary dimerization of microtubule-associated tau protein: Implications for microtubule bundling and tau-mediated pathogenesis

Kenneth J. Rosenberg, Jennifer L. Ross, H. Eric Feinstein, Stuart C. Feinstein, and Jacob Israelachvili

Proc Natl Acad Sci U S A. 2008 May 27; 105(21): 7445–7450. Published online 2008 May 21.doi: 10.1073/pnas.0802036105

PMCID: 

PMC2396711

AbstractFull TextPDF–489KSupplementary Material

18.

Cell-Cycle Markers in a Transgenic Mouse Model of Human Tauopathy : Increased Levels of Cyclin-Dependent Kinase Inhibitors p21Cip1 and p27Kip1

Patrice Delobel, Isabelle Lavenir, Bernardino Ghetti, Max Holzer, and Michel Goedert

Am J Pathol. 2006 March; 168(3): 878–887. doi: 10.2353/ajpath.2006.050540

PMCID: 

PMC1606514

AbstractFull TextPDF–4.5M

19.

Genome-wide association reveals genetic effects on human Aβ₄₂ and τ protein levels in cerebrospinal fluids: a case control study

Mi-Ryung Han, Gerard D Schellenberg, and Li-San Wang

BMC Neurol. 2010; 10: 90. Published online 2010 October 8. doi: 10.1186/1471-2377-10-90

PMCID: 

PMC2964649

AbstractFull TextPDF–2.3MSupplementary Material

20.

Phosphorylation inhibits turnover of the tau protein by the proteasome: influence of RCAN1 and oxidative stress